Searchable abstracts of presentations at key conferences in endocrinology

ea0056oc10.5 | Cardiovascular aspects of endocrine diseases | ECE2018

Increased risk of antithyroid drug-induced agranulocytosis with amiodarone

Gershinsky Michal , Lavi Idit , Shapira Chen , Gronich Naomi

Aim: Antithyroid drugs (ATD) methimazole and propylthiouracil (PTU) are the drugs of choice for treatment of hyperthyroidism. Agranulocytosisis, the most severe side effect of these medications, occurs in 0.2–0.5% of patients. ATDs are used also in patients with amiodarone-induced thyrotoxicosis (AIT). Our objective was to evaluate the risk for agranulocytosis, associated with ATDs, in patients with AIT, and to compare the risk with the risk of ATD-associated agranulocyto...